Asendis

What is it?

A TCAD preparation containing amoxapine, available in tablets of two strengths, both seven-sided, scored tablets: 50mg, orange, marked L. L50; 100mg, blue, marked LL100.

Medical Uses

Depression.

Dosage

100-150mg per day at first increasing to a maintenance dose in the region of 150-250mg. Maximum daily dose is 300mg. Elderly persons, 25mg twice a day at first increasing, after 57 days, to 50mg 3 times daily if required.

Special Care

Patients with psychoses or suicidal tendencies, elderly persons, pregnant and nursing mothers, people with cardiac disorders, epilepsy, hyperthyroidism, urine retention, closed angle glaucoma, liver disease, tumours of adrenal gland, diabetes

Avoid Use

Children, patients with recent heart attack, heart arrhythmias, heart block, porphyria (rare blood disorder).

Possible Drug and Food Interactions

Alcohol, barbiturate drugs, local anaesthetics (containing adrenaline or noradrenaline), antihypertensive and sympathomimetic drugs, anticholinergic drugs, cimetidine, oestrogens.

Known Side Effects

Anticholinergic effects including urine retention, dry mouth, constipation, blurred vision, rapid heartbeat, palpitations, nervousness, insomnia, sweating, dizziness, fatigue, weight changes, jaundice, blood changes, allergic skin rashes, changes in libido, breast enlargement and impotence.

Manufacturer

Goldshield.