Foscavir

What is it?

An Antiviral Preparation Which Is A DNA Polymerise Inhibitor, Acting In Two Stages To Inhibit The Replication Of Cytomegalovirus In AIDS. Available As A Solution Containing 24mg Foscarnet Sodium Hexahydrate Per Ml, Produced As Bottles Of Isotonic Infusion.

Medical Uses

Life-Threatening Infections Of Viral Origin Particularly Those Of The Eyes In Patients With AIDS (Cytomegalovirus Retinitis). Also, For Infections Of Mucous Membranes And Skin Caused By Herpes Simplexvirus (HSV) In Immunocompromised Or AIDS Patients, Which Have Not Responded To Treatment With Aciclovir.

Dosage

According To Manufacturer's Specifications.

Special Care

Kidney Disease - Monitor Kidney Function And Also, Blood Levels Of Electrolytes, Before And During Treatment. Patients Should Be Well- Hydrated.

Avoid Use

Pregnancy, Breast-Feeding.

Possible Drug And Food Interactions

Pentamidine Givenintravenously, Other Kidney Toxicdrugs.

Known Side Effects

Disturbance Of Kidney Function, Decreased Haemoglobin And Electrolyte Levels In Blood, Convulsions, Inflammation And Ulceration Of Genitals. See: Manufacturer's Prescribing Notes.

Manufacturer

Astrazeneca.