Franol

What is it?

A Bronchodilator Which Is An Indirect-Acting Sympathomimetic And Xanthine, Available As White Tablets Containing 11mg Of Ephedrine Hydrochloride And 120mg Of Theophylline, Marked FRANOL. Also, FRANOL PLUS, Available As White Tablets Marked FRANOL+ Containing 15mg Of Ephedrine Sulphate And 120mg Of Theophylline.

Medical Uses

Reversible Airway Obstruction In Asthma Or Chronic Bronchitis.

Dosage

Adults, 1 Tablet 3 Times Each Day, Including 1 At Bedtime, If Needed.

Special Care

Breastfeeding, Elderly Patients, Heart, Kidney Or Liver Disease, Glaucoma, Disorders Causing Fits, Adrenal Gland Tumour (Phaeochromocytoma), Enlarged Prostate Gland, Glaucoma, Stomach Ulcer, Hyperthyroidism (Over-Active Thyroid Gland).

Avoid Use

Children, Pregnancy, Disease Of The Coronary Arteries, Angina Which Is Unstable, Heart Arrhythmias, Severe High Blood Pressure, Porphyria (Rare, Inherited Metabolic Disorder Involving Porphyrins).

Possible Drug And Food Interactions

(Xanthine Component), The Following Reduce Clearance Of Xanthines: Influenza Vaccine, Oxpentifylline, Viloxazine, Interferon, Allopurinol, Clarithromycin, Methotrexate, Propanol, Disulfram, Cimetidine, Ofloxacin, Thiabendazole, Erythromycin, Carbimazole, Isoprenaline, Verapamil, Ciprofloxacin, Isoniazid, Propafenone, Diltiazem, Mexiletine, Fluconazole, Norfloxacin, Fluvoxamine, Nizatidine. The Following Increase Clearance Of Xanthines: Alcohol, Smoking, Aminoglutethimide, Ritonavir, Moracizine, Sulphinpyrazone, Rifampicin, Carbamazepine, Primidone, Barbiturates, Phenytoin, St John's Wort. Plasma Levels May Need To Be Checked And Dose Adjustments Made, If Necessary. Xanthines Also, May Interact With: Ketamine, Doxapram, 1blockers.

Known Side Effects

Low Blood Potassium Levels, Sweating, Trembling, Anxiety, Thirst, Difficulty Passing Urine, Raised Heartbeat, Flushing, Restlessness, Insomnia, Headahe, Gastrointestinal Disturbance, Nausea, Dizziness, Muscle Weakness Heart Arrhythmias.