Humulin I

What is it?

A preparation of intermediate-acting, human isophane insulin (prb), 100iu per ml, available in preloaded pens or in cartridges for use with Humapen or Autopen devices.

Medical Uses

Diabetes.

Dosage

According to individual patient requirements; usually self-administered by subcutaneous or intramuscular injection. Effects last for about 22 hours.

Special Care

Kidney or liver disease, patients transferring from animal insulins (should be warned that early signs of hypoglycaemia may not be so apparent). Infections, illnesses, stress, emotional upset, pregnancy, change in insulin source, type etc; in all these cases, dose adjustments may be needed.

Possible Drug and Food Interactions

Oral contraceptives, MAOIs, alcohol, β-blockers, corticotrophin, diuretics, corticosteroids.

Known Side Effects

Lipodystrophy (changes involving fat deposition) at injection site.

Manufacturer

Lilly.