Infanrix-HIB

What is it?

A preparation of diptheria, tetanus and whooping cough vaccine (DTPa) with inactivated surface antigen. Comprising triple antigen adsorbed onto aluminium salts containing a minimum of 30iu of diptheria toxoid, a minimum of 40iu of tetanus toxoid, acellar whooping cough vaccine comprising 25µg of pertussis toxoid, 25µg of filamentous haernagluttin and 8µg of pertactin for every 0.5ml of suspension. Also, contains 10µg of capsular polysaccharide of H. inflenzae type b, covalently bound to tetanus toxoid, per 0.5ml. Available as a suspension in vials and pellets in vials.

Medical Uses

Immunisation of children against diptheria, tetanus and whooping cough and against invasive infections caused by H. inflenzae type b.

Dosage

Infants aged 2 months, 1 x 0.5ml dose by deep intramuscular injection, repeated twice at intervals of at least 1 month.

Special Care

Epilepsy, epilepsy in family member, history of fits during fever.

Avoid Use

If child has reacted badly after previously receiving the vaccine, acute fever, incidence of encephalopathy (brain fever) within 1 week of previous vaccination with preparation containing pertussis.

Known Side Effects

Restlessness, appetite loss, headache, continuous crying, malaise, drowsiness, gastrointestinal upset, allergic symptoms. Any adverse side effects should be reported to the Committee on the Safety of Medicines (CSM).