Metenix

What is it?

A thiazide-like diuretic preparation available as blue tablets containing 5mg of metolazone marked with strength and symbol.

Medical Uses

Fluid retention, toxaemia or ascites (collection of fluid in peritoneal cavity of the abdomen)of pregnancy, high blood pressure.

Dosage

Fluid retention, 5-10mg as a single daily dose with a maximum of 80mg every 24 hours; high blood pressure, 5mg each day at first reducing after 3 to 4 weeks to this dose taken every second day.

Special Care

Pregnancy, breast-feeding, elderly, liver or kidney disease, cirrhosis of the liver, gout, diabetes, systemic lupus erythematosus (SLE-an inflammatory disease of connective tissue, believed to be an autoimmune disorder). Fluid, electrolytes (salts), and glucose levels require monitoring during the course of therapy.

Avoid Use

Children, high blood calcium levels, serious liver or kidney failure, allergy to sulphonamide drugs, Addison's disease.

Possible Drug and Food Interactions

NSAIDs, carbenoxolone, lithium, barbiturates, tubocurarine, alcohol, cardiac glycosides, alcohol, corticosteroids, opioids, antidiabetic drugs.

Known Side Effects

Gastrointestinal disturbance, anorexia, sensitivity to light, disturbance of electrolyte balance and metabolism, pancreatitis, rash, impotence, blood changes, dizziness.

Manufacturer

Borg.