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What is it?

A thiazide and potassium- sparing diuretic, available as film- coated, yellow tablets marked CIBA and RC, containing 0.25mg of cyclophenthiazide and 2.5mg of amiloride.

Medical Uses

Mild to moderate high blood pressure.

Dosage

Adults, 1 or 2 tablets each day, taken in the morning.

Special Care

Pregnancy, breastfeeding, liver or kidney disease, diabetes, hyperlipidaemia (high blood lipid levels), gout, respiratory or metabolic acidosis.

Avoid Use

Children, severe kidney or liver failure, anuria (absence of urination), high blood calcium or potassium levels, Addison's disease, hyponatraemia (low blood sodium levels), high levels of uric acid in urine.

Possible Drug and Food Interactions

Ace inhibitors, other antihypertensives, lithium, digitalis, potassium supplements, potassium-sparing diuretics.

Known Side Effects

Blood changes, gout, gastrointestinal upset, fatigue, rash, sensitivity to light.

Manufacturer

Novartis.