Nebilet

What is it?

An antihypertensive and cardioselective β-blocker available as scored, white tablets containing 5mg of nebivo1o1 hydrochloride.

Medical Uses

High blood pressure.

Dosage

Adults, 5mg each day; elderly patients should receive 2.5mg at first, increasing to 5mg each day if needed.

Special Care

Pregnancy, breast-feeding, liver or kidney disease, diabetes, metabolic acidosis, poor cerebral blood supply, history of bronchospasm, those undergoing anaesthesia; patients with weak hearts should be treated with digitalis and diuretics. Drug should be stopped gradually.

Avoid Use

Children, patients with asthma, heart diseases including heart block, heart shock, slow heartbeat rate, heart failure.

Possible Drug and Food Interactions

Cardiac depressants, anaesthetics, reserpine, sedatives, class II calcium antagonists, anti- hypertensives, sympathomimetics, cimetidine, indomethacin, ergot- amine, class I antiarrhythmic drugs, verapamil, clonidine withdrawal, hypoglycaemics, rifampicin, warfarin, ibuprofen.

Known Side Effects

Sleep disturbance, cold feet and hands, slow heartbeat, fatigue on exercise, wheeziness, heart failure, gastro-intestinal disorders; dry eyes or skin rash (stop use gradually), hair loss, low blood pressure, thrombocytopenia (abnormal decline in blood platelets).