Surmontil

What is it?

A TCAD preparation available as white tablets in strengths of 10mg and 25mg containing trimipramine (as maleate), both marked with strength and SURMONTIL. Also, SURMONTIL CAPSULES, white/green containing 50mg of trimipramine as maleate, marked SU50.

Medical Uses

Depression and/or anxiety agitation, disturbance of sleep.

Dosage

Adults, mild or moderate symptoms, 50 to 75mg as single dose, 2 hours before going to bed. Continue for a minimum of 3 weeks. Moderate to severe symptoms, 75mg each day at first under specialist supervision, gradually increasing according to need. Usual dose is in the order of 150 to 300mg each day for 1 month to 6 weeks, then reducing for maintenance once condition improves. Elderly, 10 to 25mg, 3 times each day.

Special Care

Patients with psychoses or suicidal tendencies, elderly persons, pregnant and nursing mothers, people with cardiac disorders, epilepsy, hyperthyroidism, urine retention, closed angle glaucoma, liver disease, tumours of adrenal gland, diabetes.

Avoid Use

Children, patients with recent heart attack, heart arrhythmias, heart block, porphyria (rare blood disorder).

Possible Drug and Food Interactions

Alcohol, barbiturate drugs, local anaesthetics (containing adrenaline or noradrenaline), antihypertensive and sympathomimetic drugs, anticholinergic drugs, cimetidine, oestrogens.

Known Side Effects

Anticholinergic effects including urine retention, dry mouth, constipation, blurred vision, rapid heartbeat, palpitations, nervousness, insomnia, sweating, dizziness, fatigue, weight changes, jaundice, blood changes, allergic skin rashes, changes in libido, breast enlargement and impotence.

Manufacturer

Aventis.